RB1 Mouse anti-Human, Clone: OTI1C3, lyophilized, TrueMAB
Mouse Monoclonal Antibody
Manufacturer: OriGene CF805648
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCORb is a tumor suppressor nuclear phosphoprotein capable of binding to DNA. It is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus-16 E. Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth. Aberrations in the RB gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.
|Human recombit protein fragment corresponding to amino acids 309-590 of human RB1 produced in E.coli.|
|Immunohistochemistry (Paraffin), Western Blot|
|PBS with 8% trehalose and no preservative; pH 7.3|
|OSRC, PPP1R130, RB, p105-Rb, pRb, pp110|
|-20° C, Avoid Freeze/Thaw Cycles|
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