Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Invitrogen™ RBL1 Monoclonal Antibody (KAB6)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA112362

Catalog No. 01-674-287


Only null left
Add to Cart

Description

Description

RBL1 Monoclonal Antibody for Western Blot

RB-like 1 is similar in sequence and possibly function to the product of the retinoblastoma 1 (RB1) gene. The RB1 gene product is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and RB-like 1 can form a complex with adenovirus E1A protein and SV40 large T-antigen, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein, it is thought that RB-like 1 may also be a tumor suppressor.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

RBL1
Monoclonal
Unconjugated
RBL1
107 kDa retinoblastoma-associated protein; AW547426; CP107; DNA-binding protein RFX5; MGC40006; p107; pRb1; RB transcriptional corepressor like 1; Rbl1; Regulatory factor X 5; regulatory factor X, 5 (influences HLA class II expression); regulatory factor X5; retinoblastoma-like 1; retinoblastoma-like 1 (p107); retinoblastoma-like protein 1; RFX5
Mouse
Protein A/G
RUO
19650, 5933, 680111
-20°C, Avoid Freeze/Thaw Cycles
Liquid
Western Blot
KAB6
PBS with 0.08% sodium azide
P28749, Q64701
RBL1
GST fusion protein to the N terminus of p107.
100 μg
Primary
Human, Mouse, Rat
Antibody
IgG1
Product Suggestions

Product Suggestions

Videos
Safety and Handling

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
SDS
Documents

Documents

Product Certifications
Promotions

Promotions

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.