RBL2 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 272511AP150UL

Catalog No. 50-173-5621

Description

Two retinoblastoma-related proteins, p107 and pRb2/p130 are structurally and functionally similar to the product of the retinoblastoma gene (pRb/p105). Like pRb they bind transforming proteins of DNA tumor viruses through a particular region called the "pocket domain". Both proteins play a fundamental role in growth control. The highest percentage of undetectable levels and the tightest inverse correlation with the histological grading and with PCNA expression in the most aggressive tumor types were found for pRb2/p130, which may suggest an important role for this protein in the pathogenesis and progression of lung cancer.

Specifications

• Antigen: RBL2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RBL2
• Gene Alias: P130, pRb2, Rb2, RBL2, RBR 2, retinoblastoma like 2 (p130), Retinoblastoma like protein 2
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5934
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.4 mg/mL
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Accession No.: Q08999
• Gene Symbols: RBL2
• Immunogen: RBL2 Fusion Protein Ag25087
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG