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RBM22 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. 501733725 Shop All Proteintech Group Inc Products
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50-173-3725 150 μL
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Catalog No. 50-173-3725 Supplier Proteintech Group Inc Supplier No. 221031AP150UL
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Rabbit Polyclonal Antibody

RanGAP1, is a homodimeric 65-kD polypeptide that specifically induces the GTPase activity of RAN, but not of RAS by over 1, 000-fold. RanGAP1 is the immediate antagonist of RCC1, a regulator molecule that keeps RAN in the active, GTP-bound state. The RANGAP1 gene encodes a 587-amino acid polypeptide. The sequence is unrelated to that of GTPase activators for other RAS-related proteins, but is 88% identical to Fug1, the murine homolog of yeast Rna1p. RanGAP1 and RCC1 control RAN-dependent transport between the nucleus and cytoplasm. RanGAP1 is a key regulator of the RAN GTP/GDP cycle.

Specifications

Antigen RBM22
Applications Western Blot
Classification Polyclonal
Concentration 0.65 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene RBM22
Gene Accession No. Q4V7D7, Q8BHS3, Q9NW64
Gene Alias fSAP47, Pre mRNA splicing factor RBM22, RBM22, RNA binding motif protein 22, ZC3H16
Gene Symbols RBM22
Host Species Rabbit
Immunogen RBM22 Fusion Protein Ag17315
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 307410, 55696, 66810
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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