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Invitrogen™ RCCD1 Polyclonal Antibody
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Catalog No. PIPA558881
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100 μL
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PIPA558881 100 μL
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Catalog No. PIPA558881 Supplier Invitrogen™ Supplier No. PA558881
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: ELEPRLLEAL QGLVMAEVAA GGWHSVCVSE TGDIYIWGWN ESGQLALPTR NLAEDGETVA REATELNEDG SQVKRTGG Highest antigen sequence identity to the following orthologs: Mouse - 73%, Rat - 77%.

Plays a role in transcriptional repression of satellite repeats, possibly by regulating H3K36 methylation levels in centromeric regions together with KDM8 (PubMed:24981860). Possibly together with KDM8, is involved in proper mitotic spindle organization and chromosome segregation (PubMed:24981860). Plays a role in regulating alpha-tubulin deacetylation and cytoskeletal microtubule stability, thereby promoting cell migration and TGF-beta-induced epithelial to mesenchymal transition (EMT), potentially through the inhibition of KDM8 (PubMed:28455245).
TRUSTED_SUSTAINABILITY

Specifications

Antigen RCCD1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.6 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene RCCD1
Gene Accession No. A6NED2
Gene Alias RCC1 domain containing 1; RCC1 domain-containing protein 1; RCCD1
Gene Symbols RCCD1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human RCCD1. Recombinant protein control fragment (Product #RP-98163).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 91433
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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