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Invitrogen™ RCN3 Polyclonal Antibody
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Catalog No. PIPA598793
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100 μg
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PIPA598793 100 μg
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Catalog No. PIPA598793 Supplier Invitrogen™ Supplier No. PA598793
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Rabbit Polyclonal Antibody

RCN3 Polyclonal Antibody for Western Blot, IHC (P), ELISA

Probable molecular chaperone assisting protein biosynthesis and transport in the endoplasmic reticulum (PubMed:16433634, PubMed:28939891). Required for the proper biosynthesis and transport of pulmonary surfactant-associated protein A/SP-A, pulmonary surfactant-associated protein D/SP-D and the lipid transporter ABCA3. By regulating both the proper expression and the degradation through the endoplasmic reticulum-associated protein degradation pathway of these proteins plays a crucial role in pulmonary surfactant homeostasis. Has an anti-fibrotic activity by negatively regulating the secretion of type I and type III collagens (PubMed:28939891). This calcium-binding protein also transiently associates with immature PCSK6 and regulates its secretion (PubMed:16433634). [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen RCN3
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene RCN3
Gene Accession No. Q8BH97, Q96D15
Gene Alias 6030455P07Rik; D530026G20Rik; D7Ertd671e; EF-hand calcium-binding protein RLP49; Rcn3; reticulocabin; reticulocalbin 3; reticulocalbin 3, EF-hand calcium binding domain; reticulocalbin-3; RLP49; UNQ239/PRO272
Gene Symbols RCN3
Host Species Rabbit
Immunogen Recombinant Human Reticulocalbin-3 protein (71-161AA).
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 52377, 57333
Target Species Human, Mouse
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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