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Active Motif REC. POLYNUCLEOSOMES (H3.3)1MG

Supplier: Active Motif 31868

Active Motif's Recombinant Polynucleosomes (H3.3) consists of 5000 bp of DNA (plasmid) and two molecules each of histones H2A that includes amino acids 1-130 (end) (accession number NM_003512), H2B that includes amino acids 1-126 (end) (accession number NM_003518), H3.3 that includes amino acids 1-136 (end) (accession number NM_005324), and H4 that includes amino acids 1-103 (end) (accession number NM_003548). Recombinant Polynucleosomes (H3.3) was generated in E. coli and has an observed molecular weight of 108 kDa. Nucleosomes comprise the smallest subunit of chromatin; they consist of 147 bp of DNA wrapped around an octamer of core histone proteins (H2A, H2B, H3 and H4). Therefore, nucleosomes are more physiologically relevant substrates than histones and histone-derived peptides for use in in vitro studies.
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