R&D Systems™ Recombinant Canine CTLA-4 Fc Chimera

Catalog No.	Quantity
10954CT100	100 μg

Catalog No. 10954CT100 Supplier R&D Systems™ Supplier No. 10954CT100

Description

Recombinant Protein

Measured by its ability to inhibit IL-2 secretion by stimulated Jurkat human acute T cell leukemia cells. Linsley, P.S. et al. (1991) J. Exp. Med. 174:561. The ED50 for this effect is 30.0-300 ng/mL.

Specifications

• Accession Number: NP_001003106.1
• For Use With (Application): Bioactivity
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS.
• Gene ID (Entrez): 1493
• Molecular Weight (g/mol): MolecularWeight-observed: 48-60 kDa, under reducing conditions.; MolecularWeight-theroretical: 40 kDa
• Quantity: 100 μg
• Source: Chinese Hamster Ovary cell line, CHO-derived canine CTLA-4 protein Lys36-Asp161
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
• Endotoxin Concentration: <0.10 EU / 1 μg of the protein by the LAL method.
• Gene Alias: CD, CD152, CD152 antigen, CD152IDDM12, CD28, celiac disease 3, CELIAC3, CTLA4, CTLA-4, cytotoxic T-lymphocyte antigen 4, cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4, cytotoxic T-lymphocyte-associated protein 4, cytotoxic T-lymphocyte-associated serine esterase-4, GRD4, GSE, ICOS, ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4
• Conjugate: Unconjugated
• Reconstitution: Reconstitute at 100 μg/mL in PBS.
• Purity or Quality Grade: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
• Protein: CTLA-4