R&D Systems™ Recombinant Canine Tie-2 Fc Chimera Protein

Catalog No.	Quantity
10720T2050	50 μg

Catalog No. 10720T2050 Supplier R&D Systems™ Supplier No. 10720T2050

Description

Recombinant Protein

Measured by its binding ability in a functional ELISA. When Recombinant Canine Tie-2 Fc Chimera (Catalog # 10720-T2) is immobilized at 0.5 μg/mL (100 μL/well), Recombinant Human Angiopoietin-2 (Catalog # 623-AN ) binds with an ED50 of 0.40-3.60 ng/mL.

Specifications

• Accession Number: XP_005626754.1
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
• Gene ID (Entrez): 7010
• Molecular Weight (g/mol): M.W.-observed: 115-135 kDa, under reducing conditions, M.W.-theroretical: 107 kDa
• Quantity: 50 μg
• Source: Mouse myeloma cell line, NS0-derived canine Tie-2 proteinCanine Tie-2 (Ala23-Lys746) (N-terminus) Accession # XP_005626754.1 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
• Endotoxin Concentration: <0.10 EU / 1 μg of the protein by the LAL method.
• Gene Alias: angiopoietin-1 receptor, CD202B, CD202b antigen, EC 2.7.10, EC 2.7.10.1, hTIE2, p140 TEK, soluble TIE2 variant 1, soluble TIE2 variant 2, TEK, TEK tyrosine kinase, endothelial, Tie2, TIE-2, TIE2CD202b, Tunica interna endothelial cell kinase, Tyrosine-protein kinase receptor TEK, Tyrosine-protein kinase receptor TIE-2, venous malformations, multiple cutaneous and mucosal, VMCM, VMCM1
• Conjugate: Unconjugated
• Reconstitution: Reconstitute at 500 μg/mL in PBS.
• Purity or Quality Grade: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
• Protein: Tie-2