R&D Systems™ Recombinant Cynomolgus CD25/IL-2R alpha Fc Protein

Description

Recombinant Protein

Measured by its ability to inhibit the IL-2-dependent proliferation of MO7e human megakaryocytic leukemic cells. The ED50 for this effect is 0.40-3.20 μg/mL.

Specifications

• Accession Number: NP_001270633.1
• For Use With (Application): Bioactivity
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS.
• Gene ID (Entrez): 3559
• Molecular Weight (g/mol): M.W.-observed: 64-73 kDa, under reducing conditions, M.W.-theroretical: 48 kDa
• Quantity: 50 μg
• Source: Human embryonic kidney cell, HEK293-derived cynomolgus monkey CD25/IL-2 R alpha protein Cynomolgus Monkey CD25/IL-2 R alpha (Glu22-Arg213) (N-terminus) Accession # NP_001270633.1 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
• Endotoxin Concentration: <0.10 EU / 1 μg of the protein by the LAL method.
• Gene Alias: CD25, CD25 antigen, IDDM10, IL-2 R alpha, IL-2 receptor subunit alpha, IL2R, IL2R alpha, IL-2 R subunit alpha, IL-2 Ra, IL2RA, IL-2-RA, IL2-RA, interleukin 2 receptor, alpha, interleukin-2 receptor subunit alpha, p55, TAC antigen, TCGFR
• Conjugate: Unconjugated
• Reconstitution: Reconstitute at 500 μg/mL in PBS.
• Purity or Quality Grade: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
• Protein: CD25/IL-2 R alpha