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R&D Systems™ Recombinant Cynomolgus CD25/IL-2R alpha Fc Protein

Catalog No. 10721RL050
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50 μg
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10721RL050 50 μg
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Recombinant Protein

Measured by its ability to inhibit the IL-2-dependent proliferation of MO7e human megakaryocytic leukemic cells. The ED50 for this effect is 0.40-3.20 μg/mL.

Specifications

Accession Number NP_001270633.1
For Use With (Application) Bioactivity
Formulation Lyophilized from a 0.2 μm filtered solution in PBS.
Gene ID (Entrez) 3559
Molecular Weight (g/mol) M.W.-observed: 64-73 kDa, under reducing conditions, M.W.-theroretical: 48 kDa
Quantity 50 μg
Source Human embryonic kidney cell, HEK293-derived cynomolgus monkey CD25/IL-2 R alpha protein Cynomolgus Monkey CD25/IL-2 R alpha (Glu22-Arg213) (N-terminus) Accession # NP_001270633.1 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)
Storage Requirements Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
Endotoxin Concentration <0.10 EU / 1 μg of the protein by the LAL method.
Gene Alias CD25, CD25 antigen, IDDM10, IL-2 R alpha, IL-2 receptor subunit alpha, IL2R, IL2R alpha, IL-2 R subunit alpha, IL-2 Ra, IL2RA, IL-2-RA, IL2-RA, interleukin 2 receptor, alpha, interleukin-2 receptor subunit alpha, p55, TAC antigen, TCGFR
Conjugate Unconjugated
Reconstitution Reconstitute at 500 μg/mL in PBS.
Purity or Quality Grade >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
Protein CD25/IL-2 R alpha
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