R&D Systems™ Recombinant Cynomolgus ICOS Fc Chimera Protein

Catalog No.	Quantity
97-36C-S100	100 μg

Catalog No. 97-36C-S100 Supplier R&D Systems™ Supplier No. 9736CS100

Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility.

Measured by its binding ability in a functional ELISA. When Recombinant Cynomolgus Monkey B7-H2 (Catalog # 9327-B7 ) is coated at 0.5 μg/mL (100 μL/well), the concentration of Recombinant Cynomolgus Monkey ICOS Fc Chimera that produces 50% optimal binding response is 0.75-3.75 ng/mL.

Specifications

• Accession Number: XP_005574075
• For Use With (Application): Bioactivity
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
• Gene ID (Entrez): 29851
• Molecular Weight (g/mol): M.W. (Observed): 40-61 kDa, reducing conditions; M.W. (theoretical): 40 kDa
• Name: Activation-inducible lymphocyte immunomediatory molecule, AILIM, AILIMCD278, CD278, CD278 antigen, CRP-1, CVID1, inducible costimulator, inducible T-cell costimulator, inducible T-cell co-stimulator, MGC39850
• Quantity: 100 μg
• Source: Chinese Hamster Ovary cell line, CHO-derived cynomolgus monkey ICOS protein Cynomolgous Monkey ICOS (Glu21-Gln134) (N-terminus) Accession # XP_005574075 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
• Endotoxin Concentration: <0.10 EU / 1 μg of the protein by the LAL method.
• Conjugate: Unconjugated
• Species: Cynomolgus Monkey
• Reconstitution: Reconstitute at 500 μg/mL in PBS.
• Purity or Quality Grade: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
• Protein: ICOS