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R&D Systems™ Recombinant Cynomolgus Monkey CTLA-4 Fc Chimera Protein

Catalog No. 9336CT01M
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93-36C-T01M 1 mg
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Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility.

Measured by its binding ability in a functional ELISA. When Recombinant Cynomolgus Monkey CTLA-4 Fc Chimera is coated at 0.5 μg/mL, 100 μL/well, Recombinant Human B7-1/CD80 Fc Chimera (Catalog # 140-B1 ) binds with an ED50 of 5-30 ng/mL.

Specifications

Accession Number XP_005574071
Characterization Bioactivity
For Use With (Application) Bioactivity
Formulation Lyophilized from a 0.2 μm filtered solution in PBS.
Gene ID (Entrez) 1493
Molecular Weight (g/mol) M.W. (Observed): 46-57 kDa, reducing conditions; M.W. (theoretical): 40 kDa
Quantity 1 mg
Source Human embryonic kidney cell, HEK293-derived cynomolgus monkey CTLA-4 protein Cynomolgus Monkey CTLA-4 (Ala37-Asp161) (N-terminus) Accession # XP_005574071 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)
Storage Requirements Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
Endotoxin Concentration <0.10 EU / 1 μg of the protein by the LAL method.
Gene Alias CD, CD152, CD152 antigen, CD152IDDM12, CD28, celiac disease 3, CELIAC3, CTLA4, CTLA-4, cytotoxic T-lymphocyte antigen 4, cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4, cytotoxic T-lymphocyte-associated protein 4, cytotoxic T-lymphocyte-associated serine esterase-4, GRD4, GSE, ICOS, ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4
Product Type Recombinant Protein
Conjugate Unconjugated
Species Cynomolgus Monkey
Reconstitution Reconstitute at 1 mg/mL in PBS.
Purity or Quality Grade >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
Protein CTLA-4
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