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R&D Systems™ Recombinant Cynomolgus Monkey GITR/TNFRSF18 Fc Chimera

Catalog No. 9428GR100
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100 μg
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94-28G-R100 100 μg
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Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility.

Measured by its binding ability in a functional ELISA. When Recombinant Cynomolgus Monkey GITR/TNFRSF18 Fc Chimera is immobilized at 0.5 μg/mL, 100 μL/well, the concentration of biotinylated recombinant human GITR Ligand/TNFSF18 that produces 50% of the optimal binding response is 8-40 ng/mL.

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Ships at ambient temperature.

Specifications

Accession Number XP_005545180
For Use With (Application) Bioactivity
Formulation Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Gene ID (Entrez) 8784
Molecular Weight (g/mol) M.W. (Observed): 49-60 kDa, reducing conditions; M.W. (theoretical): 41 kDa
Quantity 100 μg
Source Chinese Hamster Ovary cell line, CHO-derived cynomolgus monkey GITR/TNFRSF18 protein Cynomolgus Monkey GITR/TNFRSF18 (Gln20-Glu155) (N-terminus) Accession # XP_005545180 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)
Storage Requirements Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
Regulatory Status RUO
Endotoxin Concentration <0.10 EU / 1 μg of the protein by the LAL method.
Gene Alias Activation-inducible TNFR family receptor, AITR
Biological Activity 8 to 40ng/mL
Product Type Recombinant protein
Conjugate Unconjugated
Species Cynomolgus Monkey
Recombinant Recombinant
Reconstitution Reconstitute at 500 μg/mL in PBS.
Purity or Quality Grade >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
Protein GITR/TNFRSF18
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