R&D Systems™ Recombinant Cynomolgus Monkey MuSK Fc Chimera Protein

Description

Measured by its binding ability in a functional ELISA. In the presence of Recombinant Human Agrin (Catalog # 6624-AG ), immobilized Recombinant Cynomolgus Monkey MuSK Fc Chimera (Catalog # 11122-MK) at 0.5 μg/mL (100 μL/well) binds Recombinant Human LRP-4 (Catalog # 5948-LR ) with an ED50 of 10.0-80.0 ng/mL.

Specifications

• For Use With (Application): Bioactivity
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
• Gene ID (Entrez): 4593
• Molecular Weight (g/mol): M.W.-observed: 85-105 kDa, under reducing conditions., M.W.-theroretical: 78 kDa
• Quantity: 50 μg
• Source: Chinese Hamster Ovary cell line, CHO-derived cynomolgus monkey MuSK protein Cyno MuSK (Leu24-Thr495) (C-terminus) Accession # XP_005581150.1 IEGRMD Human IgG1 (Pro100-Lys330) (N-terminus)
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
• Endotoxin Concentration: <0.10 EU / 1 μg of the protein by the LAL method.
• Gene Alias: EC 2.7.10, EC 2.7.10.1, MGC126323, MGC126324, muscle, skeletal, receptor tyrosine kinase, MuSK, skeletal receptor tyrosine-protein kinase
• Conjugate: Unconjugated
• Reconstitution: Reconstitute at 500 μg/mL in PBS.
• Purity or Quality Grade: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
• Protein: MuSK