R&D Systems™ Recombinant Cynomolgus OX40/TNFRSF4 Fc Chimera Protein

Catalog No.	Quantity
10-311-OX050	50 μg

Catalog No. 10-311-OX050 Supplier R&D Systems™ Supplier No. 10311OX050

Description

Measured by its binding ability in a functional ELISA.

Measured by its binding ability in a functional ELISA. When Recombinant Human OX40 Ligand/TNFSF4 (Catalog # 1054-OX ) is immobilized at 250 ng/mL, the concentration of Recombinant Cynomolgus Monkey OX40/TNFRSF4 Fc Chimera (Catalog# 10311-OX) that produces 50% optimal binding response is found to be approximately 5-30 ng/mL.

Specifications

• Accession Number: XP_005545179
• For Use With (Application): Bioactivity
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with trehalose.
• Gene ID (Entrez): 7293
• Molecular Weight (g/mol): M.W. (Observed): 62-72 kDa, under reducing conditions; M.W. (theoretical): 47 kDa
• Name: ACT-135, ACT35 antigen, ACT35ATC35 antigen, CD134, CD134 antigen, Ly-70, OX40 cell surface antigen, OX40 homologue, OX40L receptor, OX40lymphoid activation antigene ACT35, TAX transcriptionally-activated glycoprotein 1 receptor, tax-transcriptionally activated glycoprotein 1 receptor, TNFRSF4, tumor necrosis factor receptor superfamily member 4, tumor necrosis factor receptor superfamily, member 4, Txgp1, TXGP1L, TXGP1LOX40 antigen
• Quantity: 50 μg
• Source: Human embryonic kidney cell, HEK293-derived cynomolgus monkey OX40/TNFRSF4 protein Cynomolgus Monkey OX40/TNFRSF4 (Leu29-Ala216) (N-terminus) Accession # XP_005545179 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
• Endotoxin Concentration: <0.10 EU / 1 μg of the protein by the LAL method.
• Conjugate: Unconjugated
• Species: Cynomolgus Monkey
• Reconstitution: Reconstitute at 200 μg/mL in PBS.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with trehalose.
• Endotoxin Level: <0.10 EU per 1 μg of the protein by the LAL method.
• Purity or Quality Grade: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
• Protein: OX40/TNFRSF4