R&D Systems™ Recombinant Cynomolgus/Rhesus VSIG8 Fc Chimera Protein

Description

Measured by its ability to inhibit anti-CD3 antibody induced IL-2 or IFN-gamma secretion by human T cells. The ED50 for this effect 0.500-10.0 μg/mL.

Specifications

• Accession Number: XP_028702448.1
• For Use With (Application): Bioactivity
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
• Gene ID (Entrez): 391123
• Molecular Weight (g/mol): M.W.-observed: 56-63 kDa, under reducing conditions., M.W.-theroretical: 54 kDa
• Quantity: 50 μg
• Source: Chinese Hamster Ovary cell line, CHO-derived VSIG8 protein Cynomolgus Monkey/Rhesus Macaque VSIG8 (Val24-Gly265) (C-terminus) Accession # XP_028702448.1 IEGRMD Human IgG1 (Pro100-Lys330) (N-terminus)
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
• Endotoxin Concentration: <0.10 EU / 1 μg of the protein by the LAL method.
• Gene Alias: V-set and immunoglobulin domain containing 8
• Conjugate: Unconjugated
• Reconstitution: Reconstitute at 250 μg/mL in PBS.
• Purity or Quality Grade: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
• Protein: VSIG8