R&D Systems™ Recombinant Human Active SHP-1 (aa 205-595) Protein

Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility.

Measured by its ability to dephosphorylate a tyrosine residue in a peptide containing the EGFR Y992 phosphorylation site (Catalog # ES006 ). The specific activity is >40 μmol/min/mg, as measured under the described conditions.

Specifications

• Accession Number: P29350
• For Use With (Application): Enzyme Activity
• Formulation: Supplied as a 0.2 μm filtered solution in Tris, NaCl, Glycerol and DTT.
• Gene ID (Entrez): 5777
• Molecular Weight (g/mol): M.W. (Observed): 40-46 kDa, reducing conditions; M.W. (theoretical): 46 kDa
• Name: SHP-1
• Quantity: 10 μg
• Source: E. coli-derived human SHP-1 protein Ala205-Lys595, with an N-terminal Met and 6-His tag (C-terminal variants predicted)
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -70°C as supplied. 3 months, -70°C under sterile conditions after opening.
• Gene Alias: HCP, HCPH, HPTP1C, PTP1C, PTP-1C, PTPN6, SHP1, SHP-1L, SH-PTP1
• Gene Symbol: PTPN6
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Purity or Quality Grade: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
• Protein: SHP-1