R&D Systems™ Recombinant Human BMP-2/BMP-7 Heterodimer Protein

Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility. Applications: Bioactivity

Measured by its ability to induce alkaline phosphatase production by ATDC5 mouse chondrogenic cells. Nakamura, K. et al. (1999) Exp. Cell Res. 250:351. The ED50 for this effect is 15.0-120 ng/mL.

Specifications

• Formulation: Supplied as 0.2 μm filtered solution in 30%(v/v) Acetonitrile and 0.1%(v/v) TFA with 50 μg BSA / 1 μg as a carrier protein.
• Gene ID (Entrez): 650
• Molecular Weight (g/mol): 12.9 kDa (BMP-2), 15.8 kDa (BMP-7)
• Name: BMP-2/BMP-7 Heterodimer
• Quantity: 10 μg
• Source: E. coli-derived human BMP-2/BMP-7 Heterodimer protein, (N-terminus) Human BMP-2 (Ala284-Arg396) Accession &Num; NP_001191 Human BMP-7 (Ser293-His431) Accession &Num; NP_001710 (C-terminus)
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -70 °C as supplied. 1 month, 2°C to 8°C under sterile conditions after opening. 3 months, -20°C to -70°C under sterile conditions after opening.
• Structural Form: Disulfide-linked heterodimer
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Purity or Quality Grade: >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.