R&D Systems™ Recombinant Human BTN2A2/Butyrophilin 2A2 Fc Protein

Description

Learn More About B7-related Butryophilins as Immune Modulators View Webinar

Measured by its ability to inhibit anti-CD3 antibody induced IL-2 secretion in human T lymphocytes. The ED50 for this effect is 0.1-0.5 μg/mL.

Specifications

• Accession Number: Q8WVV5
• For Use With (Application): Bioactivity
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS.
• Gene ID (Entrez): 10385
• Molecular Weight (g/mol): M.W. (theoretical): 50 kDa
• Quantity: 50 μg
• Source: Human embryonic kidney cell, HEK293-derived human BTN2A2/Butyrophilin 2A2 protein Human BTN2A2 (Gln33-Val237) (N-terminus) Accession # Q8WVV5 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
• Endotoxin Concentration: <0.10 EU / 1 μg of the protein by the LAL method.
• Gene Alias: BTF2, BTF2BT2.2butyrophilin 2, BTN2, Butyrophilin 2, butyrophilin subfamily 2 member A2, butyrophilin, subfamily 2, member A2, FLJ41908
• Common Name: BTN2A2/Butyrophilin 2
• Gene Symbol: BTN2A2
• Biological Activity: Measured by its ability to inhibit anti-CD3 antibody induced IL-2 secretion in human T lymphocytes. The ED50 for this effect is typically 0.1-0.5μg/mL.
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Reconstitution: Reconstitute at 100 μg/mL in PBS.
• Expression System: Human embryonic kidney cell, HEK293-derived Human BTN2A2 (Gln33-Val237) Accession # Q8WVV5, N-terminus; IEGRMD; Human IgG1 (Pro100-Lys330), C-terminus
• Purity or Quality Grade: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
• Protein: BTN2A2/Butyrophilin 2