R&D Systems™ Recombinant Human CD117/c-kit Fc Chimera Protein

Catalog No.	Quantity
10961SR050	50 μg

Catalog No. 10961SR050 Supplier R&D Systems™ Supplier No. 10961SR050

Description

Recombinant Protein

Measured by its ability to inhibit SCF-dependent proliferation of TF-1 human erythroleukemic cells. Kitamura, T. et al. (1989) J. Cell Physiol. 140:323. The ED50 for this effect is 30.0-180 ng/mL.

Specifications

• Accession Number: P10721.1
• For Use With (Application): Bioactivity
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS.
• Gene ID (Entrez): 3815
• Molecular Weight (g/mol): MolecularWeight-observed: 100-120 kDa, under reducing conditions.; MolecularWeight-theroretical: 82 kDa
• Quantity: 50 μg
• Source: Chinese Hamster Ovary cell line, CHO-derived human CD117/c-kit protein Human SCFR (Gln26-Thr520) (N-terminus) Accession # P10721.1 IEGRMD Human IgG1 Fc (Pro100-Lys330) (C-terminus)
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
• Endotoxin Concentration: <0.10 EU / 1 μg of the protein by the LAL method.
• Gene Alias: CD117, CD117 antigen, ckit, C-Kit, EC 2.7.10, EC 2.7.10.1, KIT, PBT, piebald trait, Proto-oncogene c-Kit, proto-oncogene tyrosine-protein kinase Kit, SCF R, SCFR, SCFRmast/stem cell growth factor receptor, soluble KIT variant 1, Tyrosine-protein kinase Kit, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein
• Conjugate: Unconjugated
• Reconstitution: Reconstitute at 500 μg/mL in PBS.
• Purity or Quality Grade: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
• Protein: CD117/c-kit