R&D Systems™ Recombinant Human CD31/PECAM-1 Fc Chimera Protein

Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility.

The Recombinant Human CD31/PECAM-1 Fc Chimera Protein is derived from HEK293. The Recombinant Human CD31/PECAM-1 Fc Chimera Protein has been validated for the following applications: Bioactivity.

Specifications

• For Use With (Application): Bioactivity
• Gene ID (Entrez): 5175
• Molecular Weight (g/mol): Theoretical M.W.: 91kDa
• Quantity: 50 μg
• Source: Human embryonic kidney cell,HEK293-derived human CD31/PECAM-1 protein, (N-terminus) Human CD31/PECAM-1 (Gln28-Lys600) Accession &Num; P16284 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70° C as supplied. 1 month, 2 to 8° C under sterile conditions after reconstitution. 3 months, -20 to -70° C under sterile conditions after reconstitution.
• Endotoxin Concentration: <0.10 EU per 1μg of the protein by the LAL method.
• Gene Alias: adhesion molecule, CD31, CD31 antigen, CD31/EndoCAM, EndoCAM, FLJ34100, FLJ58394, GPIIA', PECA1, PECAM1, PECAM-1, PECAM-1, CD31/EndoCAM, platelet endothelial cell adhesion molecule, platelet endothelial cell adhesion molecule-1, platelet/endothelial cell adhesion molecule
• Common Name: CD31/PECAM-1
• Gene Symbol: PECAM1
• Biological Activity: Measured by the ability of the immobilized protein to support the adhesion of HUVEC human umbilical vein endothelial cells. Bird, I.N. et al. (1999) J. Cell Sci . 112:1989. The ED50 for this effect is typically 1-6μg/mL.
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Expression System: Human embryonic kidney cell, HEK293-derived Human CD31/PECAM-1 (Gln28-Lys600) Accession # P16284, N-terminus; IEGRMD; Human IgG1 (Pro100-Lys330), C-terminus
• Purity or Quality Grade: >95%, by SDS-PAGE with Silver Staining