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R&D Systems™ Recombinant Human DCC Protein

Catalog No. 8637DC050
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8637DC050 50 μg
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Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility.

The Recombinant Human DCC Protein is derived from HEK293. The Recombinant Human DCC Protein has been validated for the following applications: Bioactivity.

Specifications

Accession Number P43146
For Use With (Application) Bioactivity
Gene ID (Entrez) 1630
Molecular Weight (g/mol) Observed M.W.: 123-138kDa, reducing conditions, Theoretical M.W.: 119kDa
Quantity 50 μg
Source Human embryonic kidney cell,HEK293-derived human DCC protein Phe32-Asn1097,with a C-terminal 6-His tag
Storage Requirements Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70° C as supplied. 1 month, 2 to 8° C under sterile conditions after reconstitution. 3 months, -20 to -70° C under sterile conditions after reconstitution.
Endotoxin Concentration <0.10 EU per 1μg of the protein by the LAL method.
Gene Alias Colorectal cancer suppressor, CRC18, CRCR1, deleted in colorectal cancer protein, deleted in colorectal carcinoma, IGDCC1colorectal tumor suppressor, Immunoglobulin superfamily DCC subclass member 1, immunoglobulin superfamily, DCC subclass, member 1, netrin receptor DCC, Tumor suppressor protein DCC
Common Name DCC
Gene Symbol DCC
Biological Activity Measured by its binding ability in a functional ELISA. When Recombinant Human DCC was immobilized at 1μg/mL (100μL/well), it binds Recombinant Mouse Netrin-1. The concentration of Recombinant Mouse Netrin-1 that produces 50% of the optimal binding response is approximately 5-30ng/mL.
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Expression System Human embryonic kidney cell, HEK293-derived Phe32-Asn1097, with a C-terminal 6-His tag
Purity or Quality Grade >90%, by SDS-PAGE with Silver Staining
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