R&D Systems™ Recombinant Human DNAM-1/CD226 Fc Chimera Protein

Description

Extensive quality control produces lot-to-lot consistency that instills confidence in results and ensures reproducibility. Applications: Binding Activity

Measured by its binding ability in a functional ELISA. When Recombinant Human DNAM-1/CD226Fc Chimera is immobilized at 1 μg/mL, 100 μL/well, it binds Biotinylated Recombinant Human CD155/PVR Fc Chimera (Catalog # BT9174) with an ED50 of 3-18 ng/mL.

Specifications

• Accession Number: Q15762
• For Use With (Application): Binding Activity
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS.
• Gene ID (Entrez): 10666
• Molecular Weight (g/mol): M.W. (Observed): 75-80 kDa, reducing conditions; M.W. (theoretical): 53 kDa (monomer)
• Name: DNAM-1/CD226 Fc Chimera
• Quantity: 50 μg
• Source: Mouse myeloma cell line, NS0-derived human DNAM-1/CD226 protein Human DNAM-1/CD226 (Glu19-Asn247) (N-terminus) Accession # Q15762 HIEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
• Structural Form: Disulfide-linked homodimer
• Endotoxin Concentration: <0.10 EU / 1 μg of the protein by the LAL method.
• Gene Symbol: CD226
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Reconstitution: Reconstitute at 100 μg/mL in sterile PBS.
• Purity or Quality Grade: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Protein: DNAM-1/CD226