R&D Systems™ Recombinant Human EMMPRIN/CD147 Fc Chimera (NS0) Protein

Catalog No.	Quantity
972EMN050	50 μg

Catalog No. 972EMN050 Supplier R&D Systems™ Supplier No. 972EMN050

Description

Isoform 2. aa 22-205

Measured by the ability of the immobilized protein to induce active MMP-1 secretion by NHLF human normal lung fibroblasts. The ED50 for this effect is 2-8 μg/mL. Measured by its binding ability in a functional ELISA with Recombinant SARS-CoV-2 Spike RBD Fc Chimera (Catalog # 10499-CV ).

Specifications

• Accession Number: NP_001309172.1
• For Use With (Application): Bioactivity
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
• Gene ID (Entrez): 682
• Molecular Weight (g/mol): M.W. (Observed): 60 - 65 kDa, under reducing conditions.
• Name: EMMPRIN/CD147 Fc Chimera
• Quantity: 50 μg
• Source: Mouse myeloma cell line, NS0-derived human EMMPRIN/CD147 protein Human EMMPRIN/CD147 (Thr25-His205) (C-terminus) Accession # NP_001309172.1 DIEGRMD Human IgG1 (Pro100-Lys330) 6-His tag (N-terminus)
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
• Structural Form: Disulfide-linked homodimer
• Endotoxin Concentration: <0.10 EU / 1 μg of the protein by the LAL method.
• Gene Symbol: BSG
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Reconstitution: Reconstitute at 100 μg/mL in sterile PBS.
• Purity or Quality Grade: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Protein: EMMPRIN/CD147