R&D Systems™ Recombinant Human Fc gamma RIIIA/CD16a (V176F) Protein

Catalog No.	Quantity
8894FC050	50 μg

Catalog No. 8894FC050 Supplier R&D Systems™ Supplier No. 8894FC050

Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility. Applications: Bioactivity

The Recombinant Human Fc gamma RIIIA/CD16a (V176F) Protein is derived from HEK293. The Recombinant Human Fc gamma RIIIA/CD16a (V176F) Protein has been validated for the following applications: Bioactivity.

Specifications

• Accession Number: P08637
• For Use With (Application): Bioactivity
• Gene ID (Entrez): 2214
• Molecular Weight (g/mol): Observed M.W.: 43-58kDa, reducing conditions, Theoretical M.W.: 23kDa
• Quantity: 50 μg
• Source: Human embryonic kidney cell,HEK293-derived human Fc gamma RIIIA/CD16a protein Gly17-Gln208,with a C-terminal 6-His tag
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70° C as supplied. 1 month, 2 to 8° C under sterile conditions after reconstitution. 3 months, -20 to -70° C under sterile conditions after reconstitution.
• Endotoxin Concentration: <0.10 EU per 1μg of the protein by the LAL method.
• Gene Alias: CD16a, CD16a antigen, CD16FCRIIIA, Fc fragment of IgG, low affinity IIIa, receptor (CD16a), Fc fragment of IgG, low affinity IIIa, receptor for (CD16), Fc gamma receptor III-A, FCG3, Fc-gamma receptor III-2 (CD 16), Fc-gamma receptor IIIb (CD16), Fc-gamma RIII, Fc-gamma RIIIa, Fc-gamma RIII-alpha, FCGR3, FCGR3A, FCGRIII, FcgRIIIA, FCR-10, FcRIII, FcRIIIa, IGFR3FcgammaRIIIA, immunoglobulin G Fc receptor III, low affinity III, receptor for (CD16), low affinity immunoglobulin gamma Fc region receptor III-A, neutrophil-specific antigen NA
• Common Name: Fc gamma RIIIA/CD16a
• Gene Symbol: FCGR3A
• Biological Activity: Measured by its binding ability in a functional ELISA. When Recombinant Human Fc gamma RIIIa/CD16a (V176F) was immobilize on a Ms x PolyHis coated plate, it binds biotinylated Human IgG. The concentration of biotinylated Human IgG that produces 50% of the optimal binding response is approximately 0.5-2.5μg/mL.
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Expression System: Human embryonic kidney cell, HEK293-derived Gly17-Gln208, with a C-terminal 6-His tag
• Purity or Quality Grade: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining