R&D Systems™ Recombinant Human Flt-3 Ligand/FLT3L (E. coli) Protein

Catalog No.	Quantity
30-8FK-E050	50 μg
30-8FK-E100	100 μg

Catalog No. 30-8FK-E050 Supplier R&D Systems™ Supplier No. 308FKE050

Description

E. coli-derived human Flt-3 Ligand/FLT3L protein

• Flt‑3 Ligand, also known as FL, is an alpha -helical cytokine that promotes the differentiation of multiple hematopoietic cell lineages
• Flt‑3 Ligand induces the expansion of monocytes and immature dendritic cells as well as early B cell lineage differentiation
• It synergizes with IL-3, GM-CSF, and SCF to promote the mobilization and myeloid differentiation of hematopoietic stem cells
• It cooperates with IL-2, -6, -7, and -15 to induce NK cell development and with IL-3, -7, and -11 to induce terminal B cell maturation
• Animal studies also show Flt‑3 Ligand to reduce the severity of experimentally induced allergic inflammation

Specifications

• Accession Number: P49771.1
• For Use With (Application): Bioactivity
• Gene ID (Entrez): 2323
• Molecular Weight (g/mol): 18 kDa
• Purification Method: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining
• Quantity: 50 μg
• Source: E. coli-derived human Flt-3 Ligand protein Thr27-Ala181
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to -70°C under sterile conditions after reconstitution.
• Endotoxin Concentration: <0.10 EU per 1 μg of the protein by the LAL method
• Conjugate: Unconjugated
• Reconstitution: Reconstitute at 100-500 μg/mL in PBS
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS