R&D Systems™ Recombinant Human Gas6 Protein

Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility. Applications: Bioactivity

The Recombinant Human Gas6 Protein is derived from NS0. The Recombinant Human Gas6 Protein has been validated for the following applications: Bioactivity.

Specifications

• Accession Number: NP_000811
• For Use With (Application): Bioactivity
• Gene ID (Entrez): 2621
• Molecular Weight (g/mol): Observed M.W.: 70-85kDa, reducing conditions, Theoretical M.W.: 70.5kDakDa
• Quantity: 50 μg
• Source: Mouse myeloma cell line,NS0-derived human Gas6 protein Ala49-­Ala678, with a C-­terminal 6-His tag
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70° C as supplied. 1 month, 2 to 8° C under sterile conditions after reconstitution. 3 months, -20 to -70° C under sterile conditions after reconstitution.
• Endotoxin Concentration: <1.0 EU per 1μg of the protein by the LAL method.
• Gene Alias: AXLLG, AXLLGAXL stimulatory factor, AXSFAXL receptor tyrosine kinase ligand, DKFZp666G247, FLJ34709, GAS-6, growth arrest-specific 6, growth arrest-specific protein 6
• Common Name: Gas6
• Gene Symbol: GAS6
• Biological Activity: Measured by its ability to down regulate the expression of Axl in DU145 human prostate carcinoma cells. Mishra, A. et al. (2012) Mol. Cancer Res. 10:703. The ED50 for this effect is typically 25-150ng/mL
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Expression System: Mouse myeloma cell line, NS0-derived Ala49-­Ala678, with a C-­terminal 6-His tag
• Purity or Quality Grade: >90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining