R&D Systems™ Recombinant Human ICOS (aa 21-140) mFc Chimera Protein, CF

Catalog No.	Quantity
11-423-CS050	50 μg

Catalog No. 11-423-CS050 Supplier R&D Systems™ Supplier No. 11423CS050

Description

Measured by its binding ability in a functional ELISA. Recombinant Human ICOS mFc Chimera (Catalog # 11423-CS) binds to Recombinant Human B7-H2 Fc Chimera Protein (Catalog # 165-B7 ) with a ED50 of 1.50-15.0 ng/mL.

Specifications

• Accession Number: Q9Y6W8.1
• For Use With (Application): Bioactivity
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
• Gene ID (Entrez): 29851
• Molecular Weight (g/mol): M.W. (Observed): 54-60 kDa, under reducing conditions., M.W. (Theroretical): 41 kDa
• Quantity: 50 μg
• Source: Chinese Hamster Ovary cell line, CHO-derived human ICOS protein Human ICOS (Glu21-Lys140) (N-terminus) Accession # Q9Y6W8.1 IEGRMD Mouse IgG1 (Pro100-Lys330) (C-terminus)
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
• Endotoxin Concentration: <0.10 EU per 1 μg of the protein by the LAL method.
• Gene Alias: Activation-inducible lymphocyte immunomediatory molecule, AILIMCD278, CD278 antigen, CVID1, inducible costimulator, inducible T-cell costimulator, inducible T-cell co-stimulator, MGC39850
• Conjugate: Unconjugated
• Reconstitution: Reconstitute at 250 μg/mL in PBS.
• Purity or Quality Grade: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
• Protein: ICOS