R&D Systems™ Recombinant Human ICOS Fc Chimera Biotinylated Protein

Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility.

Measured by its binding ability in a functional ELISA. When Recombinant Human B7-H2 Fc Chimera Recombinant Human B7-H2 Fc Chimera (Catalog # 165-B7 ) is immobilized at 0.1 μg/mL (100 μL/well), Biotinylated Recombinant Human ICOS Fc Chimera binds with an ED50 of 1-6 ng/mL.

Specifications

• Accession Number: Q9Y6W8
• For Use With (Application): Bioactivity
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
• Gene ID (Entrez): 29851
• Molecular Weight (g/mol): M.W. (theoretical): 40 kDa (unlabeled)
• Name: Activation-inducible lymphocyte immunomediatory molecule, AILIM, AILIMCD278, CD278, CD278 antigen, CRP-1, CVID1, inducible costimulator, inducible T-cell costimulator, inducible T-cell co-stimulator, MGC39850
• Quantity: 50 μg
• Source: Mouse myeloma cell line, NS0-derived human ICOS protein Human ICOS (Glu21-Phe141) Accession # Q9Y6W8 IEGRMD Human IgG1 (Pro100-Lys330) N-terminus C-terminusBiotinylated via sugars
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
• Endotoxin Concentration: <0.10 EU / 1 μg of the protein by the LAL method.
• Conjugate: Biotin
• Species: Human
• Reconstitution: Reconstitute at 400 μg/mL in PBS.
• Purity or Quality Grade: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
• Protein: ICOS