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R&D Systems™ Recombinant Human IGFBP-3 Protein

Catalog No. 8874B3025
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8874B3025 25 μg
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Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility.

The Recombinant Human IGFBP-3 Protein is derived from Sf 9 (baculovirus). The Recombinant Human IGFBP-3 Protein has been validated for the following applications: Bioactivity.

Specifications

Accession Number P17936
For Use With (Application) Bioactivity
Gene ID (Entrez) 3486
Molecular Weight (g/mol) Observed M.W.: 34-41kDa, reducing conditions, Theoretical M.W.: 29kDa
Quantity 25 μg
Source Spodoptera frugiperda,Sf 9 (baculovirus)-derived human IGFBP-3 protein Gly28-Lys291 Accession &Num; P17936
Storage Requirements Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70° C as supplied. 1 month, 2 to 8° C under sterile conditions after reconstitution. 3 months, -20 to -70° C under sterile conditions after reconstitution.
Endotoxin Concentration <0.10 EU per 1μg of the protein by the LAL method.
Gene Alias acid stable subunit of the 140 K IGF complex, binding protein 29, binding protein 53, growth hormone-dependent binding protein, IBP-3, IBP3BP-53, IGF-binding protein 3, IGFBP3, IGFBP-3, insulin-like growth factor binding protein 3, insulin-like growth factor-binding protein 3
Common Name IGFBP-3
Gene Symbol IGFBP3
Biological Activity Measured by its ability to inhibit the biological activity of IGF-I or IGF-II on MCF-7 human breast cancer cells. Karey, K.P. et al. (1988) Cancer Research 48:4083. The ED50 for this effect is typically 0.03-0.15μg/mL in the presence of 14ng/mL Recombinant Human IGF-II.
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Expression System Spodoptera frugiperda, Sf 9 (baculovirus)-derived Gly28-Lys291 Accession # P17936
Purity or Quality Grade >95%, by SDS-PAGE with Silver Staining
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