R&D Systems™ Recombinant Human IL-10 R alpha Protein

Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility.

The Recombinant Human IL-10 R alpha Protein is derived from HEK293. The Recombinant Human IL-10 R alpha Protein has been validated for the following applications: Bioactivity.

Specifications

• Accession Number: Q13651
• For Use With (Application): Bioactivity
• Gene ID (Entrez): 3587
• Molecular Weight (g/mol): Observed M.W.: 38-52kDa, reducing conditions, Theoretical M.W.: 24kDa
• Name: IL-10R alpha
• Quantity: 50 μg
• Source: Human embryonic kidney cell,HEK293-derived human IL-10 R alpha protein His22-Asn235
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70° C as supplied. 1 month, 2 to 8° C under sterile conditions after reconstitution. 3 months, -20 to -70° C under sterile conditions after reconstitution.
• Endotoxin Concentration: <0.10 EU per 1μg of the protein by the LAL method.
• Gene Alias: CD210 antigen, CDw210a, HIL-10R, IBD28, IL-10 receptor subunit alpha, IL10R alpha, IL-10R subunit 1, IL-10R1, IL10RA, IL-10RA, IL10RIL-10R subunit alpha, interleukin 10 receptor, alpha, interleukin-10 receptor alpha chain, Interleukin-10 receptor subunit 1, interleukin-10 receptor subunit alpha
• Common Name: IL-10 R alpha
• Gene Symbol: IL10RA
• Biological Activity: Measured by its ability to inhibit IL-10-dependent proliferation of MC/9-2 mouse mast cells. Thompson-Snipes, L. et al. (1991) J. Exp. Med. 173:507. The ED50 for this effect is typically 0.05-0.25μg/mL in the presence of 2ng/mL of Recombinant Human IL-10.
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Expression System: Human embryonic kidney cell, HEK293-derived His22-Asn235
• Purity or Quality Grade: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining