R&D Systems™ Recombinant Human IL-10 R beta Fc Chimera Protein, CF

Catalog No.	Quantity
11-460-RB100	100 μg

Catalog No. 11-460-RB100 Supplier R&D Systems™ Supplier No. 11460RB100

Description

CHO expressed

Measured by its binding ability in a functional ELISA. Recombinant Human IL-10 R beta Fc Chimera (Catalog # 11460-RB) binds Recombinant Human IL-28 R alpha/IFN-lambda R1 Fc Chimera (Catalog # 5260-MR ) in the presence of Recombinant Human IL-28B/IFN-lambda 3 (Catalog # 5259-IL/CF ) with an ED50 of 0.250-3.00 μg/mL.

Specifications

• Accession Number: Q08334.2
• For Use With (Application): Bioactivity
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS.
• Gene ID (Entrez): 3588
• Molecular Weight (g/mol): MolecularWeight-observed: 72-82 kDa, under reducing conditions., MolecularWeight-theroretical: 50 kDa
• Quantity: 100 μg
• Source: Chinese Hamster Ovary cell line, CHO-derived human IL-10 R beta protein Human IL-10 R beta (Met20-Ser220) (N-terminus) Accession # Q08334.2 GGIEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to -70°C under sterile conditions after reconstitution.
• Endotoxin Concentration: <0.10 EU per 1 μg of the protein by the LAL method.
• Gene Alias: CDw210b, CDw210b antigen, CRF2-4IL-10R subunit 2, CRFB4, CRFB4human transmembrane receptor protein; cytokine receptor10CDW210B, D21S58, D21S66, IBD25, IL-10 receptor subunit beta, IL10R beta, IL-10R2, IL-10R2IL-10R subunit beta, IL10RB, IL-10RB, interleukin 10 receptor, beta, Interleukin-10 receptor subunit 2, interleukin-10 receptor subunit beta, member 4
• Conjugate: Unconjugated
• Reconstitution: Reconstitute at 500 μg/mL in PBS.
• Purity or Quality Grade: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
• Protein: IL-10 R beta