R&D Systems™ Recombinant Human IL-17A (Human Cell-expressed) Protein

Description

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• Measured by its ability to induce CXCL1/GRO alpha secretion in HT-29 human colon adenocarcinoma cells.
• The ED50 for this effect is 0.12 to 1.2 ng/mL.
• Measured by its ability to induce IL-6 secretion by NIH-3T3 mouse embryonic fibroblast cells.

Specifications

• Accession Number: Q16552
• For Use With (Application): Bioactivity
• Gene ID (Entrez): 3605
• Molecular Weight (g/mol): 15.1 kDa (monomer)
• Name: CTLA8, CTLA-8, CTLA8cytotoxic T-lymphocyte-associated serine esterase 8, Cytotoxic T-lymphocyte-associated antigen 8, IL17, IL17A, IL-17A, IL-17Acytotoxic T-lymphocyte-associated protein 8, IL-17CTLA-8, IL17interleukin-17A, interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8), interleukin 17A
• Quantity: 10 μg
• Source: Human embryonic kidney cell, HEK293-derived human IL-17/IL-17A protein Gly24-Ala155
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
• Gene Symbol: IL17A
• Conjugate: Unconjugated
• Species: Human
• Reconstitution: Reconstitute at 100 μg/mL in PBS.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS.
• Endotoxin Level: <0.01 EU per 1 μg of the protein by the LAL method.
• Purity or Quality Grade: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.