R&D Systems™ Recombinant Human IL-36 beta/IL-1F8 (aa 5-157) Protein

Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility. Applications: Bioactivity

The Recombinant Human IL-36 beta/IL-1F8 (aa 5-157) Protein is derived from E. coli. The Recombinant Human IL-36 beta/IL-1F8 (aa 5-157) Protein has been validated for the following applications: Bioactivity.

Specifications

• Accession Number: NP_775270
• For Use With (Application): Bioactivity
• Formulation: Lyophilized from a 0.2μm filtered solution in PBS with Trehalose.
• Gene ID (Entrez): 27177
• Molecular Weight (g/mol): Observed M.W.: 17kDa, reducing conditions, Theoretical M.W.: 17kDa
• Quantity: 25 μg
• Source: E. coli-derived human IL-36 beta/IL-1F8 protein Arg5-Glu157
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70° C as supplied. 1 month, 2 to 8° C under sterile conditions after reconstitution. 3 months, -20 to -70° C under sterile conditions after reconstitution.
• Endotoxin Concentration: <0.10 EU per 1μg of the protein by the LAL method.
• Gene Alias: family of interleukin 1-eta, FIL1, FIL1 eta, FIL1-(ETA), FIL1H, FILI-(ETA), IL-1 eta, IL1-ETA, IL1F8, IL-1F8, IL1F8 (Canonical product IL-1F8a), IL-1F8 (FIL1-eta), IL1H2, IL-1H2, IL36 beta, IL36B, interleukin 1 family, member 8 (eta), interleukin 1, eta, Interleukin 36, Beta, Interleukin-1 eta, interleukin-1 family member 8, Interleukin-1 homolog 2, Interleukin-1 Superfamily e, Interleukin-36 Beta
• Common Name: IL-36 beta/IL-1F8
• Gene Symbol: IL36B
• Biological Activity: Measured by its ability to induce IL-8 secretion in A431 human epithelial carcinoma cells. The ED50 for this effect is typically 0.8-4.8ng/mL.
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Expression System: E. coli-derived Arg5-Glu157
• Purity or Quality Grade: >95%, by SDS-PAGE with Silver Staining