Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Recombinant Proteins
  4. 77004R050

R&D Systems™ Recombinant Human IL-4R alpha Fc Chimera Protein

Catalog No. 77004R050
Change view
Click to view available options
Quantity:
50 μg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
77-004-R050 50 μg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
This item is not returnable. View return policy
Catalog No. 77-004-R050 Supplier R&D Systems™ Supplier No. 77004R050
Only null left
Add to Cart
Add to Cart
This item is not returnable. View return policy

Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility.

The Recombinant Human IL-4 R alpha Fc Chimera Protein is derived from HEK293. The Recombinant Human IL-4 R alpha Fc Chimera Protein has been validated for the following applications: Bioactivity.

Specifications

Accession Number P24394
For Use With (Application) Bioactivity
Formulation Lyophilized from a 0.2μm filtered solution in PBS. Reconstitute at 250μg/mL in PBS.
Gene ID (Entrez) 3566
Molecular Weight (g/mol) Observed M.W.: 65-90kDa, reducing conditions, Theoretical M.W.: 51kDa (monomer)
Name IL-4R alpha
Quantity 50 μg
Source Human embryonic kidney cell,HEK293-derived human IL-4 R alpha protein, (N-terminus) Human IL-4 R alpha (Gly24-His232) Accession &Num; P24394 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)
Storage Requirements Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70° C as supplied. 1 month, 2 to 8° C under sterile conditions after reconstitution. 3 months, -20 to -70° C under sterile conditions after reconstitution.
Endotoxin Concentration <0.10 EU per 1μg of the protein by the LAL method.
Gene Alias CD124, CD124 antigen, IL-4 R alpha, IL-4 receptor subunit alpha, IL4R, IL4R alpha, IL-4R subunit alpha, IL-4RA, IL4RACD124, IL-4R-alpha, interleukin 4 receptor, interleukin-4 receptor alpha chain, interleukin-4 receptor subunit alpha
Common Name IL-4 R alpha
Gene Symbol IL4R
Biological Activity Measured by its ability to inhibit IL-4-dependent proliferation of TF-1 human erythroleukemic cells. Kitamura, T. et al. (1989) J. Cell Physiol. 140:323. The ED50 for this effect is typically 4-20ng/mL in the presence of 0.2ng/mL of Recombinant Human IL-4.
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Expression System Human embryonic kidney cell, HEK293-derived Human IL-4 R alpha (Gly24-His232) Accession # P24394, N-terminus; IEGRMD; Human IgG1 (Pro100-Lys330), C-terminus
Purity or Quality Grade >95%, by SDS-PAGE with Silver Staining
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.