R&D Systems™ Recombinant Human IL-6R alpha Fc Chimera Protein

Description

Carrier Free Recombinant Protein

Measured by its binding ability in a functional ELISA. Recombinant Human IL-6R alpha Fc Chimera (Catalog # 11399-SR) binds Biotinylated Recombinant Human IL-6 (Catalog # BT7270 ) with an ED50 of 0.750-7.50 ng/mL.

Specifications

• Accession Number: P08887.1
• For Use With (Application): Bioactivity
• Formulation: Supplied as a 0.2 μm filtered solution in PBS with Trehalose. See Certificate of Analysis for details.
• Gene ID (Entrez): 3570
• Molecular Weight (g/mol): MolecularWeight-observed: 88-99 kDa, under reducing conditions., MolecularWeight-theroretical: 65 kDa
• Quantity: 50 μg
• Source: Chinese Hamster Ovary cell line, CHO-derived human IL-6 R alpha protein Human IL-6 R alpha (Leu20-Pro365) (N-terminus) Accession # P08887.1 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after opening. 3 months, -20°C to -70°C under sterile conditions after opening.
• Endotoxin Concentration: <0.10 EU / 1 μg of the protein by the LAL method.
• Gene Alias: CD126, gp80, IL-6 R alpha, IL6Q, IL6R, IL6R alpha, IL-6 R-1, IL6RA, IL-6 RA, IL6RQ, interleukin 6 receptor
• Conjugate: Unconjugated
• Purity or Quality Grade: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
• Protein: IL-6 R alpha