R&D Systems™ Recombinant Human IL-7R alpha/CD127 Fc Chimera Protein

Catalog No.	Quantity
10531IR050	50 μg

Catalog No. 10531IR050 Supplier R&D Systems™ Supplier No. 10531IR050

Description

Extracellular domain

Measured by its binding ability in a functional ELISA. In the presence of 100 ng/mL of Recombinant Human IL-7 (Catalog # 207-IL ), Recombinant Human IL-7R alpha/CD127 (Extracellular Domain) Fc Chimera (Catalog # 10531-IR) binds with an ED50 of 5-30 ng/mL.

Specifications

• Accession Number: P16871.2
• For Use With (Application): Bioactivity
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
• Gene ID (Entrez): 3575
• Molecular Weight (g/mol): M.W.-observed: 78-100 kDa, under reducing conditions, M.W.-theoretical: 54 kDa
• Quantity: 50 μg
• Source: Chinese Hamster Ovary cell line, CHO-derived human IL-7 R alpha/CD127 protein Human IL-7 R alpha/CD127 (Gln21-Asp239) (N-terminus) Accession # P16871.2 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
• Endotoxin Concentration: <0.10 EU / 1 μg of the protein by the LAL method.
• Gene Alias: CD127, CD127 antigen, CD127ILRA, CDW127, IL-7 R alpha, IL-7 receptor subunit alpha, IL7R, IL7R alpha, IL-7 R subunit alpha, IL7RA, IL-7 RA, IL-7 R-alpha, interleukin 7 receptor, interleukin 7 receptor alpha chain, interleukin 7 receptor isoform H5-6, interleukin-7 receptor subunit alpha
• Conjugate: Unconjugated
• Reconstitution: Reconstitute at 500 μg/mL in PBS.
• Purity or Quality Grade: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
• Protein: IL-7 R alpha/CD127