R&D Systems™ Recombinant Human Integrin alpha V beta 8 Protein

Description

Extensive quality control produces lot-to-lot consistency that instills confidence in results and ensures reproducibility. Applications: Binding Activity

Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human Integrin alpha V beta 8 at 2 μg/mL can bind recombinant human Lap with an apparent Kd <0.5 nM.

Specifications

• Accession Number: NP_002201.1 (Integrin alpha V) & P26012.1 (Integrin beta 8)
• For Use With (Application): Binding Activity
• Formulation: Lyophilized from a 0.2 μm filtered solution in Tris, NaCl and MgCl2.
• Gene ID (Entrez): 3685
• Molecular Weight (g/mol): M.W. (Observed): 130-155 kDa and 85-100 kDa, reducing conditions; M.W. (theoretical): 110.5 kDa (alpha V subunit), 75.3 kDa (beta 8 subunit)
• Name: Integrin alpha V beta 8
• Quantity: 50 μg
• Source: Chinese Hamster Ovary cell line, CHO-derived human Integrin alpha V beta 8 protein Human Integrin alpha V (Phe31-Val992) (N-terminus) Accession # NP_002201.1 His-Pro GGGSGGGS Acidic Tail Human Integrin beta 8 (Glu43-Arg684) (N-terminus) Accession # P26012.1 His-Pro GGGSGGGS Basic Tail (C-terminus)
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 2 weeks, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
• Endotoxin Concentration: <0.01 EU / 1 μg of the protein by the LAL method.
• Gene Symbol: ITGAV
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Reconstitution: Reconstitute at 100 μg/mL in sterile PBS.
• Purity or Quality Grade: >90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
• Protein: Integrin alpha V beta 8