R&D Systems™ Recombinant Human Latent Activin A Protein

Catalog No.	Quantity
91-29L-A025	25 μg

Catalog No. 91-29L-A025 Supplier R&D Systems™ Supplier No. 9129LA025

Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility.

Measured by its ability to induce hemoglobin expression in K562 human chronic myelogenous leukemia cells. Schwall, R.H. et al. (1991) Method Enzymol. 198:340. The ED50 for this effect is 0.600-3.60 ng/mL.

Specifications

• Accession Number: P08476
• For Use With (Application): Bioactivity
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS.
• Gene ID (Entrez): 3624
• Molecular Weight (g/mol): M.W. (Observed): 13-16 kDa (mature) and 39 - 46 kDa (pro), reducing conditions; M.W. (theoretical): 32 kDa (pro) & 13 kDa (mature)
• Quantity: 25 μg
• Source: Chinese Hamster Ovary cell line, CHO-derived human Activin A protein Ser21-Ser426
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
• Endotoxin Concentration: <0.10 EU / 1 μg of the protein by the LAL method.
• Common Name: Activin A
• Gene Symbol: INHBA
• Biological Activity: Measured by its ability to induce hemoglobin expression in K562 human chronic myelogenous leukemia cells. Schwall, R.H. et al. (1991) Method Enzymol. 198:340. The ED50 for this effect is typically 0.6-3.6ng/mL.
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Reconstitution: Reconstitute at 100 μg/mL in PBS.
• Expression System: Chinese Hamster Ovary cell line, CHO-derived Ser21-Ser426
• Purity or Quality Grade: >90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
• Protein: Activin A