R&D Systems™ Recombinant Human MuSK Fc Chimera Protein

Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility.

Measured by its binding ability in a functional ELISA. In the presence of Recombinant Human Agrin (Catalog # 6624-AG ), immobilized Recombinant Human MuSK Fc Chimera (2 μg/mL at 100 μL/well) binds Recombinant Human LRP-4 (Catalog # 5948-LR ) with an ED50 of 5-50 ng/mL.

Specifications

• Accession Number: O15146-1
• For Use With (Application): Bioactivity
• Formulation: Lyophilized from a 0.2μm filtered solution in PBS.
• Gene ID (Entrez): 4593
• Molecular Weight (g/mol): 78 kDa
• Name: EC 2.7.10, EC 2.7.10.1, MGC126323, MGC126324, muscle, skeletal, receptor tyrosine kinase, MuSK, skeletal receptor tyrosine-protein kinase
• Quantity: 50 μg
• Source: Human embryonic kidney cell,HEK293-derived human MuSK protein, (N-terminus) Human MuSK (Leu24-Thr495) Accession &Num; O15146-1 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70° C as supplied. 1 month, 2 to 8° C under sterile conditions after reconstitution. 3 months, -20 to -70° C under sterile conditions after reconstitution.
• Endotoxin Concentration: <0.10 EU per 1μg of the protein by the LAL method.
• Conjugate: Unconjugated
• Species: Human
• Reconstitution: Reconstitute at 500μg/mL in PBS.
• Purity or Quality Grade: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie Blue Staining.