R&D Systems™ Recombinant Human Neuregulin-2/NRG2 Fc Chimera Protein

Catalog No.	Quantity
11-354-NR100	100 μg
11-354-NR01M	1 mg
11-354-NR050	50 μg

Catalog No. 11-354-NR100 Supplier R&D Systems™ Supplier No. 11354NR100

Description

Carrier Free Recombinant Protein

Measured in a serum-free cell proliferation assay using MCF-7 human breast cancer cells. Karey, K.P. et al. (1988) Cancer Research 48:4083. The ED50 for this effect is 10.0-100 ng/mL.

Specifications

• Accession Number: O14511.1
• For Use With (Application): Bioactivity
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
• Gene ID (Entrez): 9542
• Molecular Weight (g/mol): MolecularWeight-observed: 67-76 kDa, under reducing conditions., MolecularWeight-theroretical: 59 kDa
• Quantity: 100 μg
• Source: Human embryonic kidney cell, HEK293-derived human Neuregulin-2/NRG2 protein Human NRG2 (Cys112-Lys404) (N-terminus) Accession # O14511.1 GGIEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
• Endotoxin Concentration: <0.10 EU / 1 μg of the protein by the LAL method.
• Gene Alias: divergent of neuregulin-1, Don-1, DON1, HRG2, neuregulin 2, Neuregulin2, NRG2, NTAK, NTAKneural- and thymus-derived activator for ErbB kinases, pro-neuregulin-2, membrane-bound isoform, Pro-NRG2
• Conjugate: Unconjugated
• Reconstitution: Reconstitute at 500 μg/mL in PBS.
• Purity or Quality Grade: >90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
• Protein: Neuregulin-2