R&D Systems™ Recombinant Human Noggin Protein

Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility. Applications: Bioactivity

Measured by its ability to inhibit BMP-4-induced alkaline phosphatase production by ATDC5 mouse chondrogenic cells. The ED50 for this effect is 0.0200-0.160 μg/mL in the presence of 50 ng/mL of Recombinant Human BMP-4 (Catalog # 314-BP ).

Specifications

• Formulation: Lyophilized from a 0.2μm filtered solution in PBS with BSA as a carrier protein.
• Gene ID (Entrez): 9241
• Molecular Weight (g/mol): 23 kDa (monomer)
• Name: Noggin
• Quantity: 25 μg
• Source: Mouse myeloma cell line,NS0-derived human Noggin protein Gln28-Cys232
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70° C as supplied. 1 month, 2 to 8° C under sterile conditions after reconstitution. 3 months, -20 to -70° C under sterile conditions after reconstitution.
• Structural Form: Disulfide-linked homodimer
• Gene Alias: NOG, noggin, SYM1, symphalangism 1 (proximal), synostoses (multiple) syndrome 1, SYNS1, SYNS1A
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Purity or Quality Grade: 95%, by SDS-PAGE under reducing conditions and visualized by silver stain.