R&D Systems™ Recombinant Human NRG1-beta 1/HRG1-beta 1 Fc Protein, CF

Description

Fc Chimera

Measured in a serum-free cell proliferation assay using MCF-7 human breast cancer cells. Karey, K.P. et al. (1988) Cancer Research 48:4083. The ED50 for this effect is 2.00-20.0 ng/mL.

Specifications

• For Use With (Application): Bioactivity
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
• Gene ID (Entrez): 3084
• Molecular Weight (g/mol): M.W.-observed: 66-73 kDa, under reducing conditions, M.W.-theroretical: 52 kDa
• Quantity: 50 μg
• Source: Chinese Hamster Ovary cell line, CHO-derived human Neuregulin-1 beta 1/NRG1 beta 1 protein Human NRG1-beta1 (Ser 20-Lys 246) (N-terminus) Accession # NP_039250.2 GGIEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
• Endotoxin Concentration: <0.10 EU per 1μg of the protein by the LAL method.
• Gene Alias: ARIA, GGF, GGF2, HGL, HRG, HRG1, HRGA, MST131, MSTP131, NDF, neuregulin 1, Neuregulin1 beta 1, NRG1-IT2, SMDF
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Reconstitution: Reconstitute at 500μg/mL in sterile water.
• Form: Lyophilized
• Protein: Neuregulin-1 beta 1/NRG1 beta 1