R&D Systems™ Recombinant Human Osteoprotegerin/TNFRSF11B Protein

Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility.

Measured by its ability to inhibit TRAIL-mediated cytotoxicity using L-929 mouse fibroblast cells treated with TRAIL. The ED50 for this effect is 2 -10 ng/mL in the presence of 20 ng/mL Recombinant Human TRAIL/TNFSF10 (Catalog # 375-TL ).

Specifications

• Accession Number: AAB53709
• For Use With (Application): Bioactivity
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS.
• Gene ID (Entrez): 4982
• Molecular Weight (g/mol): M.W. (Observed): 54-64 kDa, reducing conditions; M.W. (theoretical): 43.6 kDa (monomer)
• Name: Osteoprotegerin/TNFRSF11B
• Quantity: 25 μg
• Source: Chinese Hamster Ovary cell line, CHO-derived human Osteoprotegerin/TNFRSF11B protein Met1-Leu401
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
• Structural Form: Oligomer
• Endotoxin Concentration: <0.10 EU / 1 μg of the protein by the LAL method.
• Gene Symbol: TNFRSF11B
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Reconstitution: Reconstitute at 100 μg/mL in PBS.
• Purity or Quality Grade: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Protein: Osteoprotegerin/TNFRSF11B