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R&D Systems™ Recombinant Human Proprotein Convertase 9/PCSK9 Protein

Catalog No. 3888SE010
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3888SE010 10 μg
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Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility. Applications: Bioactivity

Measured by its binding ability in a functional ELISA. When Recombinant Human LDL R (Catalog # 2148-LD ) is coated at 2 μg/mL, Recombinant Human Proprotein Convertase 9/PCSK9 binds with an ED50 of 70-420 ng/mL.

Specifications

Accession Number Q8NBP7
For Use With (Application) Bioactivity
Formulation Supplied as a 0.2 μm filtered solution in Tris, NaCl and Glycerol.
Gene ID (Entrez) 255738
Molecular Weight (g/mol) M.W. (Observed): 19 kDa & 66 kDa, reducing conditions; M.W. (theoretical): 14 kDa & 59 kDa
Name Proprotein Convertase 9/PCSK9
Quantity 10 μg
Source Mouse myeloma cell line, NS0-derived human Proprotein Convertase 9/PCSK9 protein Gln31-Gln152 & Ser153-Gln692, with a C-terminal 10-His tag
Storage Requirements Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20°C to -70°C as supplied. 3 months, -20°C to -70°C under sterile conditions after opening.
Structural Form Mature form & pro domain
Endotoxin Concentration <1.0 EU / 1 μg of the protein by the LAL method.
Gene Alias EC 3.4.21, EC 3.4.21.111, FH3, FH3neural apoptosis regulated convertase 1, FHCL3, HCHOLA3, hypercholesterolemia, autosomal dominant 3, LDLCQ1, NARC1, NARC-1, NARC-1convertase subtilisin/kexin type 9 preproprotein, NARC1EC 3.4.21.-, Neural apoptosis-regulated convertase 1, PC9, PCSK9, Proprotein convertase 9, proprotein convertase subtilisin/kexin type 9, Subtilisin/kexin-like protease PC9
Gene Symbol PCSK9
Conjugate Unconjugated
Recombinant Recombinant
Purity or Quality Grade >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
Protein Proprotein Convertase 9/PCSK9
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