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R&D Systems™ Recombinant Human Serpin B2/PAI-2 Protein

Catalog No. 9206PI025
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25 μg
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92-06P-I025 25 μg
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Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility.

The Recombinant Human Serpin B2/PAI-2 Protein is derived from E. coli. The Recombinant Human Serpin B2/PAI-2 Protein has been validated for the following applications: Enzyme Activity.

Specifications

Accession Number P05120
For Use With (Application) Enzyme Activity
Gene ID (Entrez) 5055
Molecular Weight (g/mol) Observed M.W.: 41kDa, reducing conditions, Theoretical M.W.: 44kDa
Quantity 25 μg
Source E. coli-derived human Serpin B2 protein Glu2-Ala65/Ala99-Pro415,with an N-terminal Met and 6-His tag
Storage Requirements Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -70° C as supplied. 3 months, -70° C under sterile conditions after opening.
Endotoxin Concentration <1.0 EU per 1μg of the protein by the LAL method.
Gene Alias HsT1201, Monocyte Arg-serpin, PAI, PAI2, PAI2Urokinase inhibitor, Placental plasminogen activator inhibitor, PLANH2, PLANH2PAI-2, plasminogen activator inhibitor 2, plasminogen activator inhibitor, type II (arginine-serpin), serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2, Serpin B2, serpin peptidase inhibitor, clade B (ovalbumin), member 2, Urokinase Inhibitor
Common Name SerpinB2
Biological Activity Measured by its ability to inhibit uPA cleavage of a peptide substrate, N-carbobenzyloxy-Gly-Gly-Arg-7-amido-4-methylcoumarin (Z-GGR-AMC). The inhibition IC50 is <15 nM, as measured under the described conditions. See Activity Assay Protocol on RnDSystems.com.
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Expression System E. coli-derived Glu2-Ala65/Ala99-Pro415, with an N-terminal Met and 6-His tag
Purity or Quality Grade >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining
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