R&D Systems™ Recombinant Human TIGIT (T103) Fc Chimera Protein

Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility.

Measured by its binding ability in a functional ELISA. When Recombinant Human CD155/PVR (Catalog # 2530-CD ) is coated at 2.5 μg/mL (100 μL/well), the concentration of Recombinant Human TIGIT Fc Chimera that produces 50% optimal binding response is typically 8-48 ng/mL.

Specifications

• Accession Number: Q495A1-1
• Characterization: Bioactivity
• For Use With (Application): Bioactivity
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS.
• Gene ID (Entrez): 201633
• Molecular Weight (g/mol): M.W. (Observed): 44-60 kDa, reducing conditions; M.W. (theoretical): 40 kDa
• Quantity: 50 μg
• Source: Human embryonic kidney cell, HEK293-derived human TIGIT protein Human TIGIT (Met22-Pro141) (N-terminus) Accession # Q495A1-1 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -70 °C under sterile conditions after reconstitution.
• Endotoxin Concentration: <0.10 EU / 1 μg of the protein by the LAL method.
• Product Type: Recombinant Protein
• Conjugate: Unconjugated
• Species: Human
• Reconstitution: Reconstitute at 500 μg/mL in PBS.
• Purity or Quality Grade: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
• Protein: TIGIT