R&D Systems™ Recombinant Human VISTA/B7-H5/PD-1H Fc Chimera Protein

Catalog No.	Quantity
71-26B-701M	1 mg

Catalog No. 71-26B-701M Supplier R&D Systems™ Supplier No. 7126B701M

Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility. Applications: Bioactivity

Measured by its ability to inhibit anti-CD3 antibody induced IL-2 secretion in human T lymphocytes. The ED50 for this effect is 1-6 μg/mL.

Specifications

• Accession Number: AAH20568
• Characterization: Bioactivity
• For Use With (Application): Bioactivity
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS.
• Gene ID (Entrez): 64115
• Molecular Weight (g/mol): M.W. (Observed): 64-75 kDa, reducing conditions; M.W. (theoretical): 44.8 kDa (monomer)
• Quantity: 1 mg
• Source: Mouse myeloma cell line, NS0-derived human VISTA/B7-H5/PD-1 H protein Human VISTA/B7-H5/PD-1 H (Phe33-Ala194) (N-terminus) Accession # AAH20568 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
• Endotoxin Concentration: <0.01 EU / 1 μg of the protein by the LAL method.
• Gene Alias: 4632428N05Rik, B7H5, B7-H5, C10orf54, chromosome 10 open reading frame 54, Dies1, Gi24, PD1H, PD-1H, platelet receptor Gi24, PP2135, SISP1, stress induced secreted protein 1
• Gene Symbol: C10orf54
• Product Type: Recombinant Protein
• Conjugate: Unconjugated
• Species: Human
• Reconstitution: Reconstitute at 200 μg/mL in PBS.
• Purity or Quality Grade: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
• Protein: VISTA/B7-H5/PD-1 H