R&D Systems™ Recombinant Mouse Caspr2 His-tag Protein

Catalog No.	Quantity
10-196-CR100	100 μg

Catalog No. 10-196-CR100 Supplier R&D Systems™ Supplier No. 10196CR100

Description

Contactin Associated Protein-Like 2 (CASPR2), also known as Cntnap2, is a neuronal type I transmembrane member of the neurexin family of adhesion molecules

• CASPR2, along with CASPR1 (or Cntnap1), is required for radical and longitudinal organization of myelinated axons
• CASPR2 is thought to be important for the control of neuron-glia interactions and is associated with alterations in synaptic structure, neuronal network activity, and an autism-related phenotype in mice

Specifications

• Accession Number: Q9CPW0
• For Use With (Application): Bioactivity
• Gene ID (Entrez): 26047
• Molecular Weight (g/mol): 138 kDa
• Purification Method: >90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining
• Quantity: 100 μg
• Source: Mouse myeloma cell line, NS0-derived mouse Caspr2 protein Ala28-Ser1262, with a C-terminal 6-His tag
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to -70°C under sterile conditions after reconstitution.
• Endotoxin Concentration: <0.10 EU per 1 μg of the protein by the LAL method
• Conjugate: Unconjugated
• Reconstitution: Reconstitute at 500 μg/mL in PBS
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose