R&D Systems™ Recombinant Mouse FCRN Heterodimer Protein

Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility.

The Recombinant Mouse FCRN Heterodimer Protein is derived from NS0. The Recombinant Mouse FCRN Heterodimer Protein has been validated for the following applications: Bioactivity.

Specifications

• Accession Number: Q6PKB0
• For Use With (Application): Bioactivity
• Gene ID (Entrez): 2217
• Molecular Weight (g/mol): Observed M.W.: 41-46kDa (mFcRN); 9 - 12kDa (m beta-2-microglobulin), Theoretical M.W.: 32kDa (mFcRN); 12kDa (m beta-2-microglobulin)
• Quantity: 50 μg
• Source: Mouse myeloma cell line,NS0-derived mouse FCRN protein Ser22-Ser301 with a C-terminal 6-His tag
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70° C as supplied. 1 month, 2 to 8° C under sterile conditions after reconstitution. 3 months, -20 to -70° C under sterile conditions after reconstitution.
• Endotoxin Concentration: <0.10 EU per 1μg of the protein by the LAL method.
• Gene Alias: alpha-chain, Fc fragment of IgG, receptor, transporter, alpha, FCGRT, FcRn, FcRn alpha chain, FCRNimmunoglobulin receptor, intestinal, heavy chain, IgG Fc fragment receptor transporter alpha chain, IgG receptor FcRn large subunit p51, major histocompatibility complex class I-like Fc receptor, Neonatal Fc receptor, neonatal Fc-receptor for Ig
• Common Name: FCRN/FCGRT
• Gene Symbol: Fcgrt
• Biological Activity: Measured by its binding ability in a functional ELISA. When Recombinant Mouse FCRN is immobilized at 0.5μg/mL (100μL/well), the concentration of human IgG that produces 50% of the optimal binding response is found to be approximately 2-10μg/mL.
• Conjugate: Unconjugated
• Species: Mouse
• Recombinant: Recombinant
• Expression System: Mouse myeloma cell line, NS0-derived Ser22-Ser301 with a C-terminal 6-His tag
• Purity or Quality Grade: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining